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Molecular diagnostics, including techniques like Polymerase Chain Reaction (PCR) and Next-Generation Sequencing (NGS), have revolutionized disease detection and genetic research. The instruments that automate these workflows rely on high-precision fluidic systems to handle valuable samples and expensive reagents for tasks like sample preparation, purification, thermal cycling, and detection. 

 

The Engineering Challenge

Pumps in molecular diagnostic instruments must deliver extremely precise, low-volume dispensing of reagents and buffers. Accuracy and repeatability are paramount to ensure the quantitative nature of tests like qPCR. Preventing cross-contamination between samples is absolutely critical to avoid false-positive results. The pumps must be compatible with a range of specialized biological buffers and reagents. Given the high cost of these tests, reliability is essential to prevent instrument downtime and the loss of irreplaceable patient samples. 

 

The Thomas & TriContinent Solutions

 

Thomas offers a range of high-precision pump technologies ideal for the demanding fluidics of molecular diagnostics. Our Peristaltic Pumps provide contamination-free, accurate dosing, making them an excellent choice for transferring master mixes and other reagents where sterility is critical. For applications requiring the absolute highest precision and the ability to handle challenging reagents without crystallization or failure, our TriContinent Syringe Pumps deliver unmatched, drift-free performance at the microliter and nanoliter scale. Engineered for millions of maintenance-free cycles, these pumps provide the reliability and consistency that high-stakes diagnostic testing demands.